Biography
Dr McHugh teaches neuroscience and statistics courses for students reading Experimental Psychology (EP) and Psychology, Philosophy and Linguistics (PPL).
Dr McHugh’s research focuses on the neurophysiological basis of learning and memory, and in particular how memories are encoded, consolidated, and expressed via the coordination of ensembles of neurons; and how different cell types and neurotransmitters influence these processes.
Selected Publications
2024
McHugh SB, Lopes-dos-Santos V, Castelli M, Gava GP, Thompson SE, Tam SKE, Hartwich K, Perry B, Toth R, Denison T, Sharott, A, Dupret D (2024). Offline hippocampal reactivation during dentate spikes supports flexible memory. Neuron 112(22): 1-14. https://doi.org/10.1016/j.neuron.2024.08.022
2024
Gava GP, Lefèvre L, Broadbelt T, McHugh SB, Lopes-dos-Santos V, Brizee D, Hartwich K, Sjoberg H, Perestenko PV, Toth, R, Sharott A, Dupret D (2024). Organizing the coactivity structure of the hippocampus from robust to flexible memory. Science 385(6713): 1120-1127. https://doi.org/10.1126/science.adk9611
2022
McHugh SB, Lopes-dos-Santos V, Gava GP, Hartwich K, Tam SKE, Bannerman DM, Dupret D (2022). Adult-born dentate granule cells promote hippocampal population sparsity. Nature Neuroscience 25(11): 1481-1491. https://doi.org/10.1038/s41593-022-01176-5
2021
Gava GP, McHugh SB, Lefevre L, Lopes-dos-Santos V, Trouche S, El-Gaby M, Schultz SR, Dupret D (2021). Integrating new memories into the hippocampal network activity space. Nature Neuroscience 24: 326–330. http://europepmc.org/abstract/med/33603228
2019
Lima J, Sharp T, Bannerman DM, McHugh SB (2019). Enhanced discriminative aversive learning and amygdala responsivity in 5-HT transporter mutant mice. Translational Psychiatry 9(1): 139. https://doi.org/10.1038/s41398-019-0476-8
2014
McHugh SB, Barkus C, Huber A, Capitao L, Lima J, Lowry J, Bannerman D (2014) Aversive prediction error signals in the amygdala. Journal of Neuroscience 34 (27): 9024-9033. https://doi.org/10.1523/JNEUROSCI.4465-13.2014
2014
Barkus C, Line SJ, Huber A, Capitao L, Lima J, Jennings K, Lowry J, Sharp T, Bannerman DM, McHugh SB (2014) Variation in serotonin transporter expression modulates fear-evoked hemodynamic responses and theta-frequency neuronal oscillations in the amygdala. Biological Psychiatry 75: 901-908. https://doi.org/10.1016/j.biopsych.2013.09.003
Positions
- Tutorial Fellow in Psychology
Subjects
- Psychology
