Biography
Dr Nicole Stoffel received her BSc and MSc degrees in Pharmaceutical Sciences from ETH Zurich, Switzerland and completed her PhD in the Laboratory of Human Nutrition at ETH Zurich. She was awarded the Swiss Foundation for Nutrition Research Award 2020 for her publications on oral iron supplementation in Lancet Hematology 2017 and in Haematologica 2020. She received the ETH Medal for her outstanding Doctoral thesis in 2018. In 2021 she was awarded the prestigious Lopez-Loreta Prize pour l’Excellence Académique for her research in the field of iron and adaptive immunity/vaccine response.
Her current research interests are optimizing oral iron supplementation regimens in pregnant women and in young infants and thereby also improving vaccine efficacy.
Selected Publications:
von Siebenthal HK, Gessler S, Vallelian F, Steinwendner J, Kuenzi U, Moretti D, Zimmermann MB, Stoffel NU. Alternate day versus consecutive day oral iron supplementation in iron-depleted women: a randomized double-blind placebo-controlled study. eClinicalMedicine 2023. https://doi.org/10.1016/j.eclinm.2023.102286
von Siebenthal HK, Moretti D, Zimmermann MB, Stoffel NU. Effect of dietary factors and time of day on iron absorption from oral iron supplements in iron deficient women. Am J Hematol 2023. https://doi.org/10.1002/ajh.26987
von Siebenthal HK, Galetti V, Zimmermann MB, Stoffel NU. Regulation of iron absorption in infants. Am J Clin Nutr 2023. https://doi.org/10.1016/j.ajcnut.2022.10.003
Stoffel NU, Zimmermann MB, Cepeda Lopez AC, Cervantes Gracia K, Lianas Cornejo D, Zeder C, Tuntipopipat S, Moungmaithong S, Densupsoontorn N, Quack-Loetscher K, Gowachirapant S, Herter-Aeberli I. Maternal iron kinetics and maternal-fetal iron transfer in normal weight and overweight pregnancy. Am J Clin Nutr 2022. https://doi.org/10.1093/ajcn/nqab406
Drakesmith H, Pasricha SR, Cabantchik I, Hershko C, Weiss G, Girelli D, Stoffel NU, Muckenthaler MU, Nemeth E, Camaschella C, Klenerman P, Zimmermann MB. Vaccine efficacy and iron deficiency: an intertwined pair? Lancet Haematol 2021. https://doi.org/10.1016/S2352-3026(21)00201-5
Frost JN, Tan TK, Abbas M, Shah A, Wideman S, Bonadonna M, Stoffel NU, et al. Hepcidin-mediated hypoferremia disrupts immune response to vaccination and infection. Med, 2021. https://doi.org/10.1016/j.medj.2020.10.004
Stoffel NU, von Siebenthal HK, Moretti D, Zimmermann MD. Oral iron supplementation in iron-deficient women: how much and how often? Molecular Aspects of Medicine, 2020. https://doi.org/10.1016/j.mam.2020.100865
Stoffel NU, Uyoga MA, Mutuku F, Frost J, Mwasi E, van der Klis FRM, et al. Effects of anaemia and iron supplementation on vaccine response: a birth cohort study and a randomized trial follow-up study in Kenyan infants. Frontiers in Immunology, 2020. https://doi.org/10.3389/fimmu.2020.01313
Stoffel NU, Cercamondi CI, Brittenham G, Zeder C, Guerts-Moespot AJ, Swinkels DW, Moretti D, Zimmermann MB. Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomized controlled trials. Lancet Hematology, 2017. https://doi.org/10.1016/S2352-3026(17)30182-5
Positions
- Associate Research Fellow in Biomedical Sciences
- Group Leader in Nutritional Physiology and Therapeutics, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science
- Senior Scientist, Department of Health Sciences and Technology, ETH Zurich
Subjects
- Biomedical Sciences
