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Dr Irem Sepil

BSc Bogazici, DPhil Oxf


Dr Sepil's research is focused on the evolutionary biology and mechanisms of male reproductive ageing and paternal age effects using the fruit fly, Drosophila melanogaster, as a model organism. She is also interested in male reproductive strategies, sexual selection, sperm competition and life history.

Selected Publications

-  Fricke C, Sanghvi K, Emery M, Lindenbaum I, Wigby S, Ramm SA & Sepil I (2023) Timeless or tainted? The effects of male ageing on seminal fluid. Frontiers in Ecology and Evolution, doi: 10.3389/fevo.2023.1066022

-  Archer R, Paniw M & Sepil I (2022) A sex-skew in life history and ageing research - the problem of missing males. Proceedings of the Royal Society B, 289:20221117

-  Bath E, Buzzoni D, Ralph T, Wigby S & Sepil I (2021) Influences of male age, mating history and starvation on female post mating aggression and feeding in Drosophila. Functional Ecology, 35:1288–1298.

-  Sepil I, Hopkins BR, Dean R, Bath E, Friedman S, Swanson B, Ostridge HJ, Harper L, Buehner NA, Wolfner MF, Konietzny R, Thezenas ML, Sandham E, Charles PD, Fischer R, Steinhauer J, Kessler BM & Wigby S (2020) Male reproductive ageing arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable in Drosophila. Proceedings of the National Academy of Sciences, 117:17094-17103

- Hopkins BR, Sepil I, Thezenas ML, Craig J, Miller T, Charles PD, Fischer R, Kessler BM, Bretman A, Pizzari T & Wigby S (2019) Divergent allocation of sperm and the seminal proteome along a competition gradient in male Drosophila melanogaster. Proceedings of the National Academy of Sciences, 201906149

-  Sepil I, Hopkins BR, Dean R, Thezenas ML, Charles PD, Konietzny R, Fischer R, Kessler BM & Wigby S (2019) Quantitative proteomics identification of seminal fluid proteins in male Drosophila melanogaster. Molecular and Cellular Proteomics, 18:S46-S58


  • Associate Research Fellow in Biology
  • Royal Society Dorothy Hodgkin Fellow, Department of Biology


  • Biology