Biography
Dr Ridley studied Biology at the University of Southampton, then trained as a Clinical Scientist in Immunology at Southampton General Hospital, during which time she completed an MSc in Medical Immunology at King’s College London. After a year monitoring clinical trials at Oxford BioMedica, she moved to the University of Oxford as a research assistant. Here she completed a DPhil in Clinical Medicine investigating T cell phenotype and function in inflammatory arthritis. Dr Ridley worked as a postdoc, also in Oxford, using cellular techniques to study Th17 cells and identify factors predicting a positive outcome to treatment in inflammatory arthritis, before moving to the medical school at Queen Mary University of London, where she leads the immunology teaching. Dr Ridley is passionate about communicating science and as a STEM ambassador works with the Centre of the Cell and in other setting to engaged students.
Selected publications:
Mimpen, J.Y., Hedley, R., Ridley, A. et al. (2023). Cellular characterisation of advanced osteoarthritis knee synovium. Arthritis Res Ther 25 (1): 154
Simone D, Penkava F, Ridley A, Sansom S, Al-Mossawi MH, Bowness P. (2021). "Single cell analysis of spondylarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fate." Commun Biol. 4(1):1395
Al-Mossawi MH, Chen L, Fang H, Ridley A, de Wit J, Yager N, Hammitzsch A, Pulyakhina I, Fairfax BP, Simone D, Yi Y, Bandyopadhyay S, Doig K, Gundle R, Kendrick B, Powrie F, Knight JC, Bowness P. (2017). "Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis." Nat Commun. 8(1):1510.
Ridley A., Hatano H., Wong-Baeza I., Shaw J., Matthews KK., Al-Mossawi H., Ladell K., Price DA., Bowness P. and Kollnberger S. (2016). "Activation-induced KIR3DL2 binding to HLA-B27 licenses pathogenic T cell differentiation in Spondyloarthritis." Arthritis Rheumatol. 68(4): 901-14
Wong-Baeza, I., Ridley, A., Shaw, J., Hatano, H., Rysnik, O., McHugh, K., Piper, C., Brackenbridge, S., Fernandes, R., Chan, A., Bowness, P., and Kollnberger, S. (2013). "KIR3DL2 Binds to HLA-B27 Dimers and Free H Chains More Strongly than Other HLA Class I and Promotes the Expansion of T Cells in Ankylosing Spondylitis." J Immunol. 190(7): 3216-24
Positions
- Lecturer in Medicine (Pathology)
Subjects
- Pre-Clinical Medicine
